ICMR to Maharashtra, Well being Information, ET HealthWorld

Lower cut off for RT-PCR test will lead to missing infections: ICMR to MaharashtraThe Indian Council of Medical Analysis (ICMR) has knowledgeable the Maharashtra authorities that it’s not in any respect advisable to make use of a decrease cycle threshold (CT) parameter in RT-PCR assessments as it’ll result in lacking a number of infectious individuals and enhance illness transmission.

Balram Bhargava, Director Basic, ICMR, in a letter to Pradeep Vyas, Principal Secretary, Well being and Household Welfare, Maharashtra, stated: “Implementing a Ct minimize off worth of 24 is under no circumstances advisable as it will result in lacking of a number of infectious individuals and elevated illness transmission.”

Bhargava was replying to a letter by Vyas on the topic. He stated the globally accepted minimize off for CT worth for Covid-19 ranges from 35-40 relying upon particular person restrictions laid down by particular person producers.

Nonetheless, the ICMR has taken inputs from totally different virology laboratories throughout the nation to reach at a single CT worth minimize off based mostly on particular person laboratory experiences.

The ICMR stated as per uniform consensus, a single minimize off of 35 with good sigmoidal actual time RT-PCR curve is suitable.

All sufferers with a CT worth of lower than or equal to 35 could also be thought of optimistic whereas these with greater than 35 could also be thought of damaging.

All samples of CT worth of lower than or equal to 35 with poor sigmoidal curve needs to be primarily retested, Bhargava stated within the letter.



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